The Hidden Struggles of Highly Sensitive People

March 16, 2025

Illness, Medications, and Self-Care

Being a Highly Sensitive Person (HSP) means experiencing the world on a deeper level—physically, emotionally, and mentally. Dr. Elaine Aron, in The Highly Sensitive Person, describes HSPs as having a finely tuned nervous system that makes them more reactive to their surroundings. This sensitivity can be both a strength and a challenge, especially when it comes to illness, medication, and personal care. Psychotherapist Robin Shapiro expands on this idea, emphasizing the impact of environmental sensitivities and the importance of trauma-informed therapy.

Getting Sick Hits Differently

Existing research supports the notion that HSPs may experience both intensified physical symptoms and emotional distress during illness, though more targeted studies are needed to comprehensively understand these interactions.  In my practice and day to day life I have noticed the impact on getting sick and the increase of either anxiety or depression in my HSP clients. 

Medications Pack a Punch

Ever felt like a small dose of medication hits you way harder than it should? You're not alone. Dr. Aron explains that HSPs often react more intensely to medications, experiencing stronger side effects from stimulants, sedatives, and even basic over-the-counter drugs. Antidepressants, for example, can feel too intense at standard doses. This means HSPs should work closely with their healthcare providers to adjust dosages and find the right balance for their sensitive system.

Skin Care and Chemical Sensitivities

HSPs often struggle with skin care products and environmental chemicals. Robin Shapiro highlights Multiple Chemical Sensitivities (MCS) as a common issue among sensitive individuals. Harsh fragrances, preservatives, and synthetic additives in skincare or household products can cause rashes, headaches, or general discomfort. Many HSPs find that switching to fragrance-free, natural, and hypoallergenic products helps avoid these reactions.

Rejection Sensitivity and the Need for Calm

HSPs also tend to experience heightened rejection sensitivity, meaning criticism, social exclusion, or even perceived disapproval can feel crushing. Their highly sensitive polyvagal system—a key part of emotional regulation—makes them more reactive to conflict and stress. This is why calm, supportive environments are essential for emotional well-being.

Both Aron and Shapiro emphasize the need for self-care and self-compassion. Therapy that validates and accommodates high sensitivity (rather than treating it as a problem) can be life-changing. Grounding techniques like mindfulness, deep breathing, and polyvagal exercises can also help regulate emotions and reduce overstimulation.

Thriving as an HSP

Living as an HSP isn’t about toughening up—it’s about understanding and honoring your unique needs. Being mindful of medication responses, choosing gentle personal care products, and creating a soothing, low-stimulation environment can help HSPs feel balanced. As Dr. Aron says, "Being highly sensitive does not at all rule out being, in your own way, a tenacious survivor." And as Robin Shapiro reminds us, "You do not have to continue to experience yourself as less than, regardless of where those messages come from."

Further Reading:


Annabelle Denmark (she/they), MA, LPC is a therapist based in Lakewood, CO, They specialize in trauma informed (Parts work, EMDR and Sensorimotor Psychotherapy) individual therapy for neurodivergent adults 

You can find them at https://www.renegadecounseling.com




June 20, 2026
As a therapist, I have heard some version of this question more times than I can : " Why do I always attract the wrong type of people? People who take and take and never give back. People who ignore me. People who treat me badly." And here is the honest answer: you don't know any better yet. Not because you're broken or oblivious — but because your nervous system is doing exactly what nervous systems do. It's keeping you in familiar territory. Familiarity Beats Safety. Every Time. This is the piece most people miss. Your nervous system isn't wired to seek out what's good for you. It's wired to seek out what's known to you. So if all you've ever known are relationships where love was conditional, where you had to earn your place, where being neglected or disrespected was just... Tuesday — then that's what your system registers as "normal." And normal feels safe, even when it isn't. Here's where it gets interesting. A lot of people who grew up in those environments discovered a workaround: give more . Give enough, and people like you. Give enough, and you stay in control. The more you do for people, the more you're needed — and being needed feels like belonging. The problem? That vibe attracts people who need to receive but can't reciprocate. And being given to ? Being truly cared for? That feels downright threatening, because it's unfamiliar. Familiarity beats safety. Every time. So How Do You Change the Template? You don't change your relationship patterns by finding better people. You change them by changing what feels normal to you. Here's how: 1. Notice what happens when you receive. Pay attention to how you feel when someone gives you a compliment, does something kind for you, or offers help. Really notice it. Most people who grew up giving first, last, and always feel deeply uncomfortable in that moment — fidgety, dismissive, quick to deflect. That discomfort is data. It's telling you that your nervous system has spent decades turning away from receiving and toward giving. 2. Start asking for things. Ask for help. Ask for support. Ask for care. And then sit with how hard that is. This isn't about becoming needy — it's about practicing something your system has been avoiding for a long time. 3. Build your tolerance for receiving, slowly. When the discomfort shows up (and it will), don't run from it. Notice it. Sit with it. Send it a little curiosity instead of judgment. If you do parts work, this is a great place to get curious about the part that goes stiff when someone is kind to you — where do you feel it in your body? Does it have an age? What does it need? Give it some compassion. It's been working very hard to keep you "safe." 4. Orient toward the people who actually show up for you. This one's simple but not easy. Start paying attention to people who offer care without expecting anything in return. Notice how it feels to be around them. Watch how they treat others. And here's the key shift: focus on who you are when you're with them — not what you can do for them. Follow the discomfort. The people who make you feel slightly squirmy because they're just... genuinely kind? Those are the people worth your attention. 5. Let it become your new normal. The more you orient your energy toward people who care for you without keeping score, the more familiar that starts to feel. Slowly, effortlessly, your template shifts. You stop scanning for ways to be useful and start noticing how you feel . That's when you know something real has changed. The Bottom Line You're not cursed. You're not a magnet for bad people. You're just running an old operating system that was built to keep you safe in an environment that wasn't. And like any operating system, it can be updated. It takes time. It takes discomfort. And it takes being willing to let people actually care for you — even when that's the scariest thing of all. That's the work. And it's worth it. Annabelle is a Licensed Professional Counselor and the owner of Renegade Counseling, a telehealth practice specializing in complex trauma, dissociation, and neurodivergent-affirming care. She works with adults across Colorado and Washington.
a small wooden mannequin
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